Ed Miliband is set to lose his seat to Nigel Farage's Reform UK at the next general election, according to new analysis. The research by Electoral Calculus based on the local election results found that the insurgent party would win 81 of the 145 Westminster constituencies where a ballot was held.

Forty-nine of the seats Reform is predicted to take are held by Labour, 19 are Tory and one is Lib Dem. Energy Secretary Mr Miliband would be among high-profile casualties with Doncaster North going to Reform.

Most of the Labour MPs are those in the Red Wall who won their seats last year.

Tory frontbenchers Victoria Atkins and Helen Whately would lose to Reform, while shadow chancellor Mel Stride's Devon Central would go to the Liberal Democrats.

Reform leader Mr Farage said: “The local election results show us that two-party politics is dead and no seat is safe. Reform can win the next general election.”

Electoral Calculus founder Martin Baxter said Reform had performed “very well” and had a “credible claim to be replacing both major parties at the moment”.

Mr Baxter told The Telegraph: “It remains to be seen whether this is a passing protest vote, or whether Reform are in for the longer term.

“Labour won 78 of these 145 seats less than a year ago at the general election. If anything like this predicted result were to happen at a general election, it would show tectonic plate movement in British politics.”

It comes after Reform made sweeping gains in the May 1 ballots, taking control of 10 local authorities and hundreds of councillors.

The party also won a fifth MP in the Runcorn and Helsby by-elections, along with two mayoral contests.